High-voltage, chaotic, and multifocal spikes of hypsarrhythmia are unique to IS.6 This pattern is markedly different from a normal EEG, as shown in these examples:
Because hypsarrhythmia plays such an important role in the diagnosis of IS, it's important to capture the pattern when it occurs. A routine EEG may not be sufficient for this purpose; you may wish to order a 24-hour inpatient EEG if you suspect a patient has IS.6
In 2012, a comprehensive set of quality-of-care indicators for the management of children with IS was developed.9
The proposed indicators can be used to assess and document variations and gaps in quality of care and inform future research and quality improvement interventions. Among these indicators is the practice of a follow-up EEG to confirm cessation of hypsarrhythmia following treatment.9
Videos about diagnosing IS and the treatment of IS with Acthar.
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H.P. Acthar® Gel (repository corticotropin injection) is indicated as monotherapy for the treatment of infantile spasms in infants and children under 2 years of age.Contraindications